Discover South Korea’s #1 Skin Trend, now at SKIN
Microneedling with Polynucleotides (Salmon DNA)
Microneedling opens the door - polynucleotides do the real repair work.
Microneedling with Salmon DNA
Microneedling with Salmon DNA is an innovative treatment where we use a polynucleotide-enriched serum as a powerful upgrade to standard microneedling. During the treatment, thousands of microchannels are created in the skin, allowing the polynucleotides to penetrate deeper and intensively activate the skin for enhanced results.
This treatment provides a significant boost on top of regular microneedling and can be added easily as an add-on during your microneedling appointment.
What is Salmon DNA (Polynucleotides)?
Polynucleotides are purified DNA fragments derived from salmon and known for their strong regenerative effect. They repair damaged skin cells, stimulate collagen and elastin production, and increase deep hydration from within. It is currently South Korea’s #1 skin booster, loved for its visible improvement in firmness, glow, and overall skin quality.This treatment provides a significant boost on top of regular microneedling and can be added easily as an add-on during your microneedling appointment.
Pricing
Consultation
Free & without obligation
Microneedling with Polynucleotides
€200
↳ Package of 5 (+1 Free)
Contact us
Get in touch to discover how our skin therapists can help you achieve a clearer, more radiant, and healthy-looking skin.
Who is Microneedling with Polynucleotides suitable for?
Polynucleotides are ideal for anyone who wants more than basic skin activation. They deliver a powerful regenerative and anti-aging boost that microneedling alone cannot achieve. This treatment is especially suitable for:
Anti-aging & skin rejuvenation
Dull, tired, or dehydrated skin
Thin or sensitive skin needing deeper repair
Anyone looking for faster, more visible results
Clear Skin
Facial Treatments
Efective Skincare
Senior Therapists
Latest Technologies
- A quote from a SKIN therapist
“What I love about using polynucleotides with microneedling is how deeply they repair the skin — much deeper than microneedling alone. The skin calms down faster, becomes firmer, and truly regenerates from within. It gives that extra anti-aging, hydration, and glow that so many clients look for. If you want more results from your microneedling treatment, this is the upgrade I always recommend.”
Winke, Skin Specialist at SKIN
Client Experiences
Read the experiences of clients who have been treated with us. Their feedback provides a clear insight into our results and approach.
Before & After: Real Results
After the treatment, the skin immediately feels more hydrated, plumper, and smoother. Over the following weeks, the deeper skin improvement continues to build: collagen production increases, the skin barrier strengthens, and the overall texture becomes visibly smoother.
For the best and longest-lasting results, we advise a course of 5 to 6 treatments.
For the best and longest-lasting results, we advise a course of 5 to 6 treatments.
Note: Results vary per person depending on skin type and the concern being treated. Consistency with homecare is essential for optimal results.
Frequently Asked Questions
We’ve answered the most frequently asked questions to help you prepare and give you a clear understanding of how we work.
Microneedling with polynucleotides is suitable for anyone looking to give their skin an intensive regeneration and rejuvenation boost. It is especially ideal for:
- Fine lines and early wrinkles
- Dull, tired, or dehydrated skin
- Reduced elasticity and skin laxity
- Pigmentation and uneven skin tone
- (Acne) scars and enlarged pores
- Sensitive or weakened skin barrier
- Skin that needs faster recovery after treatments
In short: it’s perfect for anyone who wants more than standard microneedling, with extra focus on anti-aging, hydration, and deep skin repair.
You often see results after just one treatment, the skin immediately feels more hydrated, smoother, and has a noticeable glow. However, we usually work in a treatment course, as the deeper skin improvements continue to build over the following weeks.
We generally recommend 5 to 6 treatments, spaced 3 to 4 weeks apart, to achieve the best and most long-lasting results.
We generally recommend 5 to 6 treatments, spaced 3 to 4 weeks apart, to achieve the best and most long-lasting results.
The treatment is generally well tolerated. You may experience a light tingling or prickling sensation from the microneedling, but most people find it very manageable.
The polynucleotides themselves are not painful, in fact, they have a calming and hydrating effect, which often makes the treatment feel more comfortable than standard microneedling.
If needed, we can always adjust the intensity to match your comfort level.
The polynucleotides themselves are not painful, in fact, they have a calming and hydrating effect, which often makes the treatment feel more comfortable than standard microneedling.
If needed, we can always adjust the intensity to match your comfort level.
Direct after the treatment, your skin may look a bit red, similar to a mild sunburn. This usually fades within a few hours and typically no later than 1–2 days.
Your skin will often feel immediately hydrated, smoother, and plumper thanks to the polynucleotides. You may also experience some mild warmth, sensitivity, or a slight rough/pebbly texture in the following days, this is completely normal and part of the healing process.
Then comes the glow: within a few days the skin looks fresher, smoother, and more rested, while the deeper skin improvements continue to build over the following weeks.
Your skin will often feel immediately hydrated, smoother, and plumper thanks to the polynucleotides. You may also experience some mild warmth, sensitivity, or a slight rough/pebbly texture in the following days, this is completely normal and part of the healing process.
Then comes the glow: within a few days the skin looks fresher, smoother, and more rested, while the deeper skin improvements continue to build over the following weeks.
We recommend avoiding makeup for at least 24 hours after the treatment. Your skin needs a bit of time to recover and to allow the polynucleotides to work optimally.
After 24 hours, you can wear makeup again as long as it’s non-comedogenic and your skin doesn’t feel irritated.
For the best results: the longer you keep your skin makeup-free, the better it can heal.
After 24 hours, you can wear makeup again as long as it’s non-comedogenic and your skin doesn’t feel irritated.
For the best results: the longer you keep your skin makeup-free, the better it can heal.
Polynucleotides provide the skin with a deep regeneration and repair boost. They support the recovery of damaged skin cells at the DNA level, activate collagen and elastin production, and deliver intensive hydration from within. They also have a calming and anti-inflammatory effect, helping redness subside more quickly while strengthening the skin barrier. In addition, they improve overall tone and texture, reducing pigmentation spots and creating a smoother, more even complexion. In short: polynucleotides repair, rejuvenate, and strengthen the skin in a way that standard microneedling alone cannot achieve.
Homecare helps to enhance your results and speed up the healing process. In the days following the treatment, we recommend using a gentle, non-irritating cleanser, keeping the skin well hydrated, and always wearing SPF. Active ingredients such as retinol, acids (AHA/BHA) or vitamin C should be avoided temporarily until the skin has fully recovered. With the right aftercare, your skin stays calmer, heals faster, and you’ll enjoy your results for much longer.
The main difference is that polynucleotides provide an extra regenerative and rejuvenating effect on top of what microneedling alone can achieve. Microneedling activates the skin by creating microchannels and stimulating natural collagen production. Polynucleotides take it a step further: they repair damaged skin cells at the DNA level, stimulate fibroblasts more intensively, deliver deep hydration, calm inflammation, and strengthen the skin barrier. As a result, the skin is not only activated but truly restored and renewed from within. The outcome is smoother, firmer, more even, and better-hydrated skin compared to microneedling alone.
The difference lies mainly in how the skin is improved and which skin concern the treatment is best suited for.
Microneedling with polynucleotides focuses on deep skin repair, collagen building, and hydration. Polynucleotides act as building blocks for the skin: they repair damaged cells, stimulate fibroblasts to produce more collagen, and strengthen the skin barrier. This makes the treatment especially effective for anti-aging, fine lines, skin laxity, dryness, and overall skin quality improvement.
Microneedling with exosomes works differently: exosomes are signaling molecules that tell cells what to do. They trigger repair and regeneration, calm inflammation, and accelerate healing. Because of this, exosomes are particularly suitable for sensitive skin, redness, inflammation, (acne) scars, and recovery after more intensive treatments.
In short:
Microneedling with polynucleotides focuses on deep skin repair, collagen building, and hydration. Polynucleotides act as building blocks for the skin: they repair damaged cells, stimulate fibroblasts to produce more collagen, and strengthen the skin barrier. This makes the treatment especially effective for anti-aging, fine lines, skin laxity, dryness, and overall skin quality improvement.
Microneedling with exosomes works differently: exosomes are signaling molecules that tell cells what to do. They trigger repair and regeneration, calm inflammation, and accelerate healing. Because of this, exosomes are particularly suitable for sensitive skin, redness, inflammation, (acne) scars, and recovery after more intensive treatments.
In short:
- Polynucleotides = rebuilding, rejuvenation, hydration, and firming.
- Exosomes = repair, calming, regeneration, and evening out the skin.
